Uptake of Preventive Treatment for Intestinal Schistosomiasis among School Children in Jinja District, Uganda: A Cross Sectional Study.

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dc.contributor.authorMuhumuza, Simon
dc.contributor.authorOlsen, Annette
dc.contributor.authorKatahoire, Anne
dc.contributor.authorNuwaha, Fred
dc.date.accessioned2018-05-16T07:09:28Z
dc.date.available2018-05-16T07:09:28Z
dc.date.issued2013-05-07
dc.descriptionThe study was a random sample of 1,010 children in 12 primary schools was questioned about their uptake of praziquantel, knowledge and perceptions about schistosomiasis, support for taking preventive treatment and the dangers of taking praziquantel.en_US
dc.description.abstractBackground: In Uganda, the current national health sector strategic and investment plan underscores schistosomiasis as one of the diseases targeted for elimination by the year 2015. However, uptake of treatment among school children is unknown but suspected to be low. We estimated the uptake and predictors of preventive treatment with praziquantel. Methods: In a cross sectional study carried out in Jinja district of Uganda, a random sample of 1,010 children in 12 primary schools was questioned about their uptake of praziquantel, knowledge and perceptions about schistosomiasis, support for taking preventive treatment and the dangers of taking praziquantel. The prevalence and mean intensity of infection with Schistosoma mansoni were determined. Results: Self-reported uptake of praziquantel at last mass treatment was 28.2% (95% confidence interval (CI): 22.9%–33.6%). Overall prevalence and mean intensity of S. mansoni infection was 35% (95% CI: 25.4%–37.9%) and 116.1 eggs per gram (epg) of stool (95% CI: 98.3–137.1) respectively. Uptake of praziquantel was more likely if a child was from a school with highprevalence of infection, had knowledge about schistosomiasis transmission and prevention, and reported teachers’ support to take praziquantel. Of the 285 children who took praziquantel, 142 (49.8%) developed side effects. Of the 725 children who did not take the drug, 522 (72.0%) reported fear of side effects as a major reason for non-uptake. Conclusions: Uptake of praziquantel in this population is very low. Fear of side effects of praziquantel, lack of knowledge about schistosomiasis transmission and prevention and lack of teacher support are some of the major factors associated with low uptake.en_US
dc.identifier.citationMuhumuza, Simon, Olsen, Annette, Katahoire, Anne, Nuwaha, Fred, 2013. Uptake of Preventive Treatment for Intestinal Schistosomiasis among School Children in Jinja District, Uganda: A Cross Sectional Studyen_US
dc.identifier.urihttps://hdl.handle.net/20.500.11951/224
dc.language.isoenen_US
dc.publisherPLoS ONEen_US
dc.subjectPreventive Treatmenten_US
dc.subjectIntestinal Schistosomiasisen_US
dc.subjectSchool Childrenen_US
dc.subjectJinja Districten_US
dc.subjectUgandaen_US
dc.titleUptake of Preventive Treatment for Intestinal Schistosomiasis among School Children in Jinja District, Uganda: A Cross Sectional Study.en_US
dc.typeArticleen_US
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The final, definitive version of this paper has been published in the journal.pone.0063438, Vol.8/Issue 5, May,7/2013, https://doi.org/10.1371/journal.pone.0063438; Published by PLoS ONE, All rights reserved.
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