UCU Digital Institutional Repository(UCUDIR)

Welcome to the Uganda Christian University Digital Institutional Repositoy (UCUDIR). This is the University's official Institutional Repository. It aims to collect, preserve and showcase the intellectual output of staff and students of UCU. This growing collection of research includes peer-reviewed articles, book chapters, working papers, theses, and more.

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Recent Submissions

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Malignant mixed mullerian tumor: a case report about a uterine tumor’s case
(Wolters Kluwer, 2022-05-20) Emmanuel D. Morgan; Tonny Okecha; James J. Yahaya; Emmanuel Othieno
Introduction: Malignant mixed Mullerian tumor (MMMT) is an exceedingly rare and aggressive tumor whichoccurs predominantly in postmenopausal women though it has been reported rarely in premenopausal women.Case presentation: A 54-year old nulliparous postmenopausal female presented with a 3-month history of vaginalbleeding, mild lower abdominal pain and weight loss. Ultrasound revealed markedly enlarged uterus with ahyper-echoic solid and cystic mass and a right adnexal complex mass. Total abdominal hysterectomy andbilateral salpingioopherectomy were done. Histopathological features were consistent with MMMT. The patientis currently stable after 6 cycles of adjuvant chemotherapy which consisted of paclitaxel and carboplatin.Clinical discussion: MMMT of the uterus is rare, high-grade neoplasms comprising only 1–2% of uterine cancersand 3–5% of all uterine malignancies. This tumor may arise in the ovaries, fallopian tubes and vagina. Histologically, MMMT is a biphasic tumor composed of both epithelial (carcinoma) elements and mesenchymal(sarcoma) elements; though, which component is responsible for the tumor’s aggressive biological behavior remains undetermined.Conclusion: MMMT is a rare and aggressive tumor which is commonly seen in postmenopausal women with highrate of recurrence therefore, Radical surgery and close follow-up is mandatory since the role of chemoradiotherapy remains unclear in the management of patients with this tumor. Both stage of the tumor andmyometrial invasion are considered as potential prognostic factors.
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ALK-1 positive anaplastic large cell lymphoma in sickle cell trait: a case report and review of literature
(Journal of Case Reports and Scientific Images, 2024-01-13) Omega Phillip; Gimono Martha; Peter Wasswa; Musoke Sharrif; Tonny Okecha; Mawanda Anatoli; Asiimwe Ivan; Okello Malcom Mark; Oballim John Kennedy; Ojok Peter Boii; Wanyenze Esther; Byebei Eunice; Masumba John Dalton; Nakayemba Jolive; Kyakoonye Moses; Atuhura Ronald; Nsobya George; Boaz Mwesigwa; Lukande Robert; Bukirwa Phiona; Yekosani Mitala; Gladys Adokorach; Achola Caroline; Wabinga Henry; dida Micheal; Kalungi Sam
Anaplastic large cell lymphoma (ALCL) is a rare subtype of non-Hodgkin lymphoma, with ALK-1 positive ALCL exhibiting an aggressive clinical course. However, it remains potentially curable if diagnosed in a timely manner. We present the case of a 13-year-old boy with coexisting sickle cell trait and ALK-1 positive ALCL, who presented with recurrent fever, progressive weight loss, generalized lymphadenopathy, and severe anemia. Despite aggressive supportive therapy, he succumbed within 32 hours of admission. Postmortem examination revealed extensive lymph node infiltration by tumor cells and widespread multi-organ involvement. This case underscores the diagnostic challenges associated with ALK-1 positive ALCL, particularly in pediatric patients with underlying hematologic conditions, and raises the possibility of a potential association between ALK-1 positive ALCL and sickle cell trait.
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An unusual case of mesenteric schistosomiasis presenting as bowel obstruction in a child
(ARC Journals, 2025-04-07) Omega Phillip; Musoke Sharrif; Tonny Okecha; Mawanda Anatoli; Boaz Mwesigwa; Asiimwe Ivan; Okello Malcom Mark; Gladys Adokorach; Oballim John Kennedy; Ojok Peter Boii; Wanyenze Esther; Byebei Eunice; Masumba John Dalton; Nakayemba Jolive; Kyakoonye Moses; Atuhura Ronald; Nsobya George; Lukande Robert; Bukirwa Phiona; Tumukunde Allan; Yekosani Mitala; Nabukalu Sandra; aratwebirwe Oseber; Odida Micheal; Kalungi Sam
Mesenteric schistosomiasis is a rare but significant cause of intestinal obstruction, particularly in endemic regions. We report a case of a 12-year-old boy from Masese Landing Site, Uganda, who presented with progressive abdominal distension, vomiting, and constipation—symptoms indicative of bowel obstruction. Surgical exploration revealed extensive adhesions and nodular lesions, necessitating biopsies. Histopathological examination confirmed intestinal schistosomiasis caused by Schistosoma mansoni. This case highlights the need for heightened clinical awareness, early diagnosis, and prompt intervention in endemic areas to prevent complications of chronic schistosomiasis
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Use of evidence based research in policy making in Uganda: a case of the Uganda National Grain Trade Policy
(Uganda Christian University, 2026-07-13) Solomon Grace Male
This study aimed at establishing the application of research based on evidence-in policy making in Uganda, taking a case study of the National Grain Trade policy. The study was guided by three objectives which include:(i) What evidence research informed the design for the National Grain Trade Policy of Uganda? (ii) How can policy makers better incorporate research evidence in the policy making process? (iii) What barriers can prevent access and utilization of research evidence to inform the policy making process in Uganda? The study utilized desk-based research to review existing articles, journals, and policy documents regarding the National Grain Trade policy. In objective (i) the study found that Technocrats undertook field studies and engaged stakeholders from the public and private sectors as well as international aid and development actors, asking questions and taking notes to inform the design of the National Grain Trade policy .In objective (ii)The study found that there are dozen ways policy makers can better incorporate research evidence in the policy making process some which include:(1)Strengthening structures for aggregating stakeholders’ interests and mechanisms for open circulation of ideas, (2) Improving dialogue especially in the transmission of research from researcher to decision-maker during the policy-making process, (3)Seeking, emphasising and promoting policy support, (4) Increasing trust amongst policy actors over the transparency of each part’s interests, (5)Incorporating any relevant research evidence within the decision-making process. In objective (iii) the study found that there are more than a dozen barriers that can prevent access and utilization of research evidence in the policy making process in Uganda. These barriers include: (1) Pressure to process information quickly, (2) Limited capacity, including time, and scarcer resources, (3) Evidence being ignored, (4) political pragmatics and contingencies, such as timeframes, legislative terms, institutional capacity, and unforeseen events. The study recommends increased sensitization of technocrats on the significance of evidence-based research in policy making.
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The Lord’s Resistance Army (LRA) insurgency in Uganda
(Routledge, 2024-09) David Andrew Omona; Scott N. Romaniuk
Uganda, a member of the East African community, has endured conflict within its borders for decades. Although there have been conflicts prior to contact with foreign powers, the postcolonial conflicts so far have exceeded what the country could contain within its borders. While the earlier conflicts pitted neighbouring communities against each other over space and power, the colonial and postcolonial conflicts have taken on different shades. During the expansion of British colonial rule, for example, a lot of resistance emerged in different parts. However, once they got hold of the different regions of present-day Uganda, they were able to suppress most of the conflicts. When the British passed the baton of leadership to Ugandans, the country took off in a positive direction. According to Patrick Rubaihayo (2005), soon after independence, the government embarked on transforming Ugandan society from colonial vestiges to a productive and free society. Social services, infrastructure, trade, and commerce were developed following the Uganda Peoples’ Congress (UPC) manifesto to fight ignorance, disease, and poverty.