Namirembe, Milly2026-10-072026-10-072026-09-28https://hdl.handle.net/20.500.11951/2307Postgraduate researchIn Uganda, cervical cancer continues to be a primary source of cancer-related illness and death for women. Despite the existence cervical cancer knowledge participation rates remain inadequate, largely due to widespread low awareness. This investigation assessed the effect of a nurse-led health education intervention on the understanding and behaviors of women and men regarding cervical cancer screening in Wakiso District. The research utilized a quantitative single-group design with pre- and post-test assessments, conducted across intentionally chosen churches in Bunamwaya Parish. A cohort of 245 individuals aged 21 and older, along with their spouses or partners, was recruited through purposive sampling. Information on awareness was gathered using a standardized questionnaire before and after health education intervention. The data were examined using descriptive statistics and paired t-tests. Findings indicated that the health education initiative led to a statistically significant increase in participants' knowledge levels. There were significant increases were observed in general cervical cancer knowledge (Mean difference = 0.45, t = 2.543, p = .011), screening Knowledge (Mean difference = 0.40, t = 2.969, p = .003), and age/frequency of screening knowledge (Mean difference = 0.27, t = 2.377, p = .018). These results suggest that the intervention was effective in enhancing participants' understanding of cervical cancer, and recommended screening intervals. The study concludes that health educational efforts led by nurses successfully improve community awareness, practices, and plans for engaging in cervical cancer screening. Incorporating these initiatives into broader public health approaches can reinforce preventive measures, aid earlier identification, and help reduce the impact of cervical cancer across Uganda.enAttribution-NonCommercial 3.0 United Stateshttp://creativecommons.org/licenses/by-nc/3.0/us/Cervical cancerCervical cancer knowledgeNurse-led health education interventionWomen and menPenders Health ModelDissertation