Browsing UCU School of Medicine by Issue Date
Now showing items 21-40 of 158
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Mortality by baseline CD4 cell count among HIV patients initiating antiretroviral therapy: evidence from a large cohort in Uganda.
(Lippincott Williams & Wilkins, Inc., 2011)Objective: Evaluations of CD4 cell count and other prognostic factors on the survival of HIV patients in sub-Saharan Africa are extremely limited. Funders have been reticent to recommend earlier initiation of treatment. ... -
Cohort Profile: The TASO-CAN Cohort Collaboration
(International Journal of Epidemiology, 2011)Sub-Saharan Africa has scaled-up access to combination anti-retroviral therapy (cART) at unprecedented rates, yet data on patient-related outcomes remain sparse. Representative databases that facilitate high quality ... -
Setting up a Standardized Peripheral Blood Mononuclear Cells Processing Laboratory to Support Multi-center HIV/AIDS Vaccine and Intervention Trials.
(Labmedicine, 2011)Despite infrastructure and capacity challenges in Africa, significant development has been made in the number of laboratories supporting immunological and safety studies required for large-scale HIV/AIDS vaccine or ... -
Male gender predicts mortality in a large cohort of patients receiving antiretroviral therapy in Uganda
(Journal of the International AIDS Society, 2011-01)Background: Because men in Africa are less likely to access HIV/AIDS care than women, we aimed to determine if men have differing outcomes from women across a nationally representative sample of adult patients receiving ... -
Patient satisfaction, feasibility and reliability of satisfaction questionnaire among patients with pulmonary tuberculosis in urban Uganda: a cross-sectional study
(Health Research Policy and Systems, 2011-01)Background A comprehensive understanding of the barriers to and facilitators of poor tuberculosis (TB) treatment outcome is still lacking; posing a major obstacle to finding effective solutions. Assessment of patient ... -
Density of Healthcare Providers and Patient Outcomes: Evidence from a Nationally Representative Multi-Site HIV Treatment Program in Uganda
(PLOS ONE, 2011-01-17)Objective: We examined the association between density of healthcare providers and patient outcomes using a large nationally representative cohort of patients receiving combination antiretroviral therapy (cART) in Uganda. ... -
Building capacity for HIV/AIDS program leadership and management in Uganda through mentored Fellowships.
(Taylor and Francis Online, 2011-02)Background: Around the world, health professionals and program managers are leading and managing public and private health organizations with little or no formal management and leadership training and experience. Objective: ... -
Association of aging and survival in a large HIV-infected cohort on antiretroviral therapy
(Wolters Kluwer Health, Lippincott Williams & Wilkins, 2011-03)Objective: To examine if there is a significant difference in survival between elderly (>50 years) and nonelderly adult patients receiving combination antiretroviral therapy in Uganda between 2004 and 2010. Design: ... -
ABC for people with HIV: responses to sexual behavior recommendations among people receiving antiretroviral therapy in Jinja, Uganda
(Routledge Taylor & Francis Group, 2011-03-09)People living with HIV who are taking antiretroviral therapy (ART) are increasingly involved in ‘positive prevention’ initiatives. These are generally oriented to promoting abstinence, ‘being faithful’ (partner reduction) ... -
Survival of HIV-Infected Adolescents on Antiretroviral Therapy in Uganda: Findings from a Nationally Representative Cohort in Uganda
(2011-04-29)Background Adolescents have been identified as a high-risk group for poor adherence to and defaulting from combination antiretroviral therapy (cART) care. However, data on outcomes for adolescents on cART in resource-limited ... -
Changes in sexual desires and behaviours of people living with HIV after initiation of ART: Implications for HIV prevention and health promotion
(BioMed Central Ltd., 2011-08-08)Background: As immune compromised HIV sero-positive people regain health after initiating antiretroviral treatment (ART), they may seek a return to an active 'normal' life, including sexual activity. The aim of the paper ... -
Life Expectancy of Persons Receiving Combination Antiretroviral Therapy in Low-Income Countries: A Cohort Analysis from Uganda
(Annals of Internal Medicine, 2011-08-16)Background: Little is known about the effect of combination antiretroviral therapy (cART) on life expectancy in sub-Saharan Africa. Objective: To estimate life expectancy of patients once they initiate cART in Uganda. Design: ... -
Predictive value of CD4 cell count nadir on long-term mortality in HIV-positive patients in Uganda
(Dovepress, 2012)Objective: Although international guidelines recommend initiating antiretroviral therapy (ART) when a patient’s CD4 cell count is <350 cells/μL, most patients in resource-limited settings present with much lower CD4 cell ... -
Engaging Men in Prevention and Care for HIV/AIDS in Africa
(PLOS Medicine, 2012-02-07)The HIV/AIDS response in Africa has always had a gender focus; targeted efforts have reduced the impact of the epidemic on women and children. The response has been far less successful for the treatment of men: there is ... -
Supporting Southern-led Research: Implications for North–South Research Partnerships
(Canadian Journal of Public Health, 2012-04)Background: Global health research partnerships are commonly led by Northern investigators who come from resource-rich research environments, while Southern partners participate with a paucity of research skills and ... -
Training multidisciplinary leaders for health promotion in developing countries: lessons learned
(Sage Publications, 2012-05)The global picture of maternal mortality and morbidity has changed very little over the past 20 years despite isolated (and often medically based) efforts to improve the situation. A multidisciplinary approach to this very ... -
Gendered sexual risk patterns and polygamy among HIV sero-discordant couples in Uganda
(Retrovirology, 2012-05-22)Multiple sexual partnerships and HIV sero-discordant relationships are among the most at-risk for HIV transmission. Polygamy is a common form of multiple-partnered relationships in Eastern Uganda. We investigated the ... -
The role of backward mutations on the within-host dynamics of HIV-1
(Journal of Mathematical Biology, 2012-09-06)The quality of life for patients infected with human immunodeficiency virus (HIV-1) has been positively impacted by the use of antiretroviral therapy (ART). However, the benefits of ART are usually halted by the emergence ... -
Closing the access barrier for effective anti-malarials in the private sector in rural Uganda: consortium for ACT private sector subsidy (CAPSS) pilot study
(BioMed Central Ltd, 2012-10-29)Background: Artemisinin-based combination therapy (ACT), the treatment of choice for uncomplicated falciparum malaria, is unaffordable and generally inaccessible in the private sector, the first port of call for most malaria ... -
Low nutrient intake among adult women and patients with severe tuberculosis disease in Uganda: a cross-sectional study
(BMC Public Health, 2012-12)Background: Information regarding dietary nutrient intake during tuberculosis disease is lacking. We established the relationship between disease severity or wasting during pulmonary tuberculosis and nutrient intake. Methods: ...
