Browsing School of Medicine by Title

Now showing items 122-141 of 158

    • Rapid reduction of malaria following introduction of vector control interventions in Tororo District, Uganda: a descriptive study 

      Oguttu, David W.; Matovu, Joseph K. B.; Okumu, David C.; Ario, Alex R.; Okullo, Allen E.; Opigo, Jimmy; Nankabirwa, Victoria (BioMed Central, 2017)
      Background: In 2012, Tororo District had the highest malaria burden in Uganda with community Plasmodium prevalence of 48%. To control malaria in the district, the Ministry of Health introduced universal distribution of ...

    • Rates of virological failure in patients treated in a home-based versus a facility-based HIV-care model in Jinja, southeast Uganda: a cluster-randomised equivalence trial 

      Jaffar, Shabbar; Amuron, Barbara; Foster, Susan; Birungi, Josephine; Levin, Jonathan; Namara, Geoffrey; Nabiryo, Christine; Ndembi, Nicaise; Kyomuhangi, Rosette; Opio, Alex; Bunnell, Rebecca; Tappero, Jordan W.; Mermin, Jonathan; Coutinho, Alex; Grosskurth, Heiner (Elsevier, 2009-12-19)
      Background: Identification of new ways to increase access to antiretroviral therapy in Africa is an urgent priority. We assessed whether home-based HIV care was as effective as was facility-based care. Methods: We undertook ...

    • Reduced uptake of mass treatment for schistosomiasis control in absence of food: beyond a randomized trial 

      Muhumuza, Simon; Olsen, Annette; Katahoire, Anne; Nuwaha, Fred (BioMed Central Ltd., 2015-10)
      Backgroud: Sustaining high uptake of praziquantel is key for long-term control of schistosomiasis. During mass treatment in 2013, we randomized 12 primary schools into two groups; one group received education messages for ...

    • Repeat Voluntary HIV Counseling and Testing (VCT), Sexual Risk Behavior and HIV Incidence in Rakai, Uganda 

      Matovu, Joseph K. B.; Gray, Ronald H.; Kiwanuka, Noah; Kigozi, Godfrey; Wabwire-Mangen, Fred; Nalugoda, Fred; Serwadda, David; Sewankambo, Nelson K.; Wawer, Maria J. (Springer Science+Business Media, LLC, 2006)
      We examined the effects of repeat Voluntary HIV counseling and testing (VCT) on sexual risk behaviors and HIV incidence in 6,377 initially HIV-negative subjects enrolled in a prospective STD control for HIV prevention trial ...

    • Retention in care among HIV-infected pregnant and breastfeeding women on lifelong antiretroviral therapy in Uganda: A retrospective cohort study. 

      Muhumuza, Simon; Akello, Evelyn; Kyomugisha-Nuwagaba, Charity; Baryamutuma, Rose; Sebuliba, Isaac; Lutalo, Ibrahim M.; Kansiime, Edgar; Kisaakye, Linda N.; Kiragga, Agnes N.; King, Rachel; Bazeyo, William; Lindan, Christina (PLoS ONE, 2017-12-22)
      Background: In 2013, Uganda updated its prevention of maternal-to-child transmission of HIV program to Option B+, which requires that all HIV-infected pregnant and breastfeeding women be started on lifelong antiretroviral ...

    • Risk factors associated with cystic echinococcosis in humans in selected pastoral and agro-pastoral areas of Uganda 

      Othieno, Emmanuel; Okwi, Andrew Livex; Mupere, Ezekiel; Zeyhle, Eberhard; Oba, Peter; Chamai, Martin; Omadang, Leonard; Inangolet, Francis Olaki; Siefert, Ludwing; Ejobi, Francis; Ocaido, Michael (International Journal of One Health, 2017-02)
      Aim: It was to determine the risk factors responsible of occurrence of cystic echinococcosis (CE) of humans in the pastoral and agro-pastoral (PAP) in Uganda. Materials and Methods: A cross-sectional study was conducted ...

    • Risk factors for death in children during inpatient treatment of severe acute malnutrition: a prospective cohort study 

      Rytter, Maren J H; Babirekere-Iriso, Esther; Namusoke, Hanifa; Christensen, Vibeke B; Michaelsen, Kim F; Ritz, Christian; Mortensen, Charlotte G; Mupere, Ezekiel; Friis, Henrik (The American Journal of Clinical Nutrition, 2017-02)
      Background: Children who receive in-hospital treatment of severe acute malnutrition often have high mortality rates, and the reasons are not well understood. Objective: We assessed risk factors for death in children who ...

    • Risk factors for HIV infection among circumcised men in Uganda: a case-control study 

      Ediau, Michael; Matovu, Joseph K. B.; Byaruhanga, Raymond; Tumwesigye, Nazarius M.; Wanyenze, Rhoda K. (Wiley-Blackwell, 2015-01)
      Introduction: Male circumcision (MC) reduces the risk of HIV infection. However, the risk reduction effect of MC can be modified by type of circumcision (medical, traditional and religious) and sexual risk behaviours ...

    • Risk Factors for Obstetric Fistula in Western Uganda: A Case Control Study 

      Barageine, Justus Kafunjo; Tumwesigye, Nazarius Mbona; Byamugisha, Josaphat K.; Almroth, Lars; Faxelid, Elisabeth (2014-11-17)
      Introduction: Two million women worldwide are living with genital fistula with an annual incidence of 50,000–100,000 women. Risk factors for obstetric fistula are context bound. Studies from other countries show variation ...

    • Risk Factors for Obstetric Fistula in Western Uganda: A Case Control Study 

      Barageine, Justus Kafunjo; Tumwesigye, Nazarius Mbona; Byamugisha, Josaphat K.; Almroth, Lars; Faxelid, Elisabeth (PLOS ONE, 2014-11)
      Introduction: Two million women worldwide are living with genital fistula with an annual incidence of 50,000–100,000 women. Risk factors for obstetric fistula are context bound. Studies from other countries show variation ...

    • The role of backward mutations on the within-host dynamics of HIV-1 

      Kitayimbwa, John M.; Mugisha, Joseph Y. T.; Saenz, Roberto A. (Journal of Mathematical Biology, 2012-09-06)
      The quality of life for patients infected with human immunodeficiency virus (HIV-1) has been positively impacted by the use of antiretroviral therapy (ART). However, the benefits of ART are usually halted by the emergence ...

    • Setting research priorities to improve global newborn health and prevent stillbirths by 2025 

      Yoshida, Sachiyo; Martines, José; Lawn, Joy E; Wall, Stephen; Souza, Joăo Paulo; Rudan, Igor; Cousens, Simon; Aaby, Peter; Adam, Ishag; Adhikari, Ramesh Kant; Ambalavanan, Namasivayam; Arifeen, Shams EI; Aryal, Dhana Raj; Asiruddin, Sk; Baqui, Abdullah; Barros, Aluisio JD; Benn, Christine S; Bhandari, Vineet; Bhatnagar, Shinjini; Bhattacharya, Sohinee; Bhutta, Zulfiqar A; Black, Robert E; Blencowe, Hannah; Bose, Carl; Brown, Justin; Bührer, Christoph; Carlo, Wally; Cecatti, Jose Guilherme; Cheung, Po–Yin; Clark, Robert; Colbourn, Tim; Conde–Agudelo, Agustin; Corbett, Erica; Czeizel, Andrew E; Das, Abhik; Day, Louise Tina; Deal, Carolyn; Deorari, Ashok; Dilmen, Uğur; English, Mike; Engmann, Cyril; Esamai, Fabian; Fall, Caroline; Ferriero, Donna M; Gisore, Peter; Hazir, Tabish; Higgins, Rosemary D; Homer, Caroline SE; Hoque, DE; Irgens, Lorentz; Islam, MT; Graft–Johnson, Joseph de; Joshua, Martias Alice; Keenan, William; Khatoon, Soofia; Kieler, Helle; Kramer, Michael S; Lackritz, Eve M; Lavender, Tina; Lawintono, Laurensia; Luhanga, Richard; Marsh, David; McMillan, Douglas; McNamara, Patrick J; Mol, Ben Willem J; Molyneux, Elizabeth; Mukasa, G. K; Mutabazi, Miriam; Nacul, Luis Carlos; Nakakeeto, Margaret; Narayanan, Indira; Olusanya, Bolajoko; Osrin, David; Paul, Vinod; Poets, Christian; Reddy, Uma M; Santosham, Mathuram; Sayed, Rubayet; Schlabritz–Loutsevitch, Natalia E; Singhal, Nalini; Smith, Mary Alice; Smith, Peter G; Soofi, Sajid; Spong, Catherine Y; Sultana, Shahin; Tshefu, Antoinette; Bel, Frank van; Gray, Lauren Vestewig; Waiswa, Peter; Wang, Wei; Williams, Sarah LA; Wright, Linda; Zaidi, Anita; Zhang, Yanfeng; Zhong, Nanbert; Zuniga, Isabel; Bahl, Rajiv (Journal of Global health, 2016-06)
      Background In 2013, an estimated 2.8 million newborns died and 2.7 million were stillborn. A much greater number suffer from long term impairment associated with preterm birth, intrauterine growth restriction, congenital ...

    • Setting up a Standardized Peripheral Blood Mononuclear Cells Processing Laboratory to Support Multi-center HIV/AIDS Vaccine and Intervention Trials. 

      Njai, Harr Freeya; Gombe, Ben; Khamis, Tomusange; Birungi, Josephine; Ruzagira, Eugene; Admassu, Dareskedar; Tarragona-Fiol, Tony; Porter, Kholoud; Stevens, Gwynneth; Mugisha, Joseph; Gilmour, Jill; Kamali, Anatoli; Kaleebu, Pontiano (Labmedicine, 2011)
      Despite infrastructure and capacity challenges in Africa, significant development has been made in the number of laboratories supporting immunological and safety studies required for large-scale HIV/AIDS vaccine or ...

    • Short Communication HIV Type 1 Transmitted Drug Resistance and Evidence of Transmission Clusters among Recently Infected Antiretroviral-Naive Individuals from Ugandan Fishing Communities of Lake Victoria 

      Nazziwa, Jamirah; Njai, Harr Freeya; Ndembi, Nicaise; Birungi, Josephine; Lyagoba, Fred; Gershim, Asiki; Nakiyingi-Miiro, Jessica; Nielsen, Leslie; Mpendo, Juliet; Nanvubya, Annet; Debont, Jan; Grosskurth, Heiner; Kamali, Anatoli; Seeley, Janet; Kaleebu, Pontiano (Aids Research and Human Retroviruses, 2013)
      Human immunodeficiency virus type 1 (HIV-1) prevalence and incidence in the fishing communities on Lake Victoria in Uganda are high. This population may play a role in driving the HIV epidemic in Uganda including the spread ...

    • A single-nucleotide-polymorphism real-time PCR assay for genotyping of Mycobacterium tuberculosis complex in peri-urban Kampala 

      Wampande, Eddie M.; Hatzios, Stavroula K.; Achan, Beatrice; Mupere, Ezekiel; Nsereko, Mary; Mayanja, Harriet K.; Eisenach, Kathleen; Boom, W Henry; Gagneux, Sebastien; Joloba, Moses L. (BMC Infectious Diseases, 2015-09)
      Background: Accurate and high-throughput genotyping of Mycobacterium tuberculosis complex (MTBC) may be important for understanding the epidemiology and pathogenesis of tuberculosis (TB). In this study, we report the ...

    • Social Experiences of Women with Obstetric Fistula Seeking Treatment at Mulago National Referral Hospital in Kampala, Uganda 

      Barageine, Justus Kafunjo; Marielle, Meurice; Rene, Genadry; Carol, Heimer; Galya, Ruffer (2017-08)
      BACKGROUND Obstetric fistula is a preventable and treatable condition predominately affecting women in low-income countries. Understanding the social context of obstetric fistula may lead to improved prevention and ...

    • Standardization of cytokine flow cytometry assays 

      Maecker, Holden T.; Rinfret, Aline; D'Souza, Patricia; Darden, Janice; Roig, Eva; Landry, Claire; Hayes, Peter; Birungi, Josephine; Anzala, Omu; Garcia, Miguel; Harari, Alexandre; Frank, Ian; Baydo, Ruth; Baker, Megan; Holbrook, Jennifer; Ottinger, Janet; Lamoreaux, Laurie; Epling, C. Lorrie; Sinclair, Elizabeth; Suni, Maria A.; Punt, Kara; Calarota, Sandra; El-Bahi, Sophia; Alter, Gailet; Maila, Hazel; Kuta, Ellen; Cox, Josephine; Gray, Clive; Altfeld, Marcus; Nougarede, Nolwenn; Boyer, Jean; Tussey, Lynda; Tobery, Timothy; Bredt, Barry; Roederer, Mario; Koup, Richard; Maino, Vernon C.; Weinhold, Kent; Pantaleo, Giuseppe; Gilmour, Jill; Horton, Helen; Sekaly, Rafick P. (BioMed Central Ltd., 2005-06-24)
      Background: Cytokine flow cytometry (CFC) or intracellular cytokine staining (ICS) can quantitate antigen-specific T cell responses in settings such as experimental vaccination. Standardization of ICS among laboratories ...

    • Stigma gets in my way: Factors affecting client-provider communication regarding child bearing among people living with HIV in Uganda 

      Beyeza-Kashesya, Jolly; Wanyenze, Rhoda K.; Goggin, Kathy; Finocchario-Kessler, Sarah; Woldetsadik, Mahlet Atakilt; Mindry, Deborah; Birungi, Josephine; Wagner, Glenn J. (2018-02-20)
      Introduction Many HIV-affected couples living in sub-Saharan Africa desire to have children, but few quantitative studies have examined support for their childbearing needs. Our study explored client-provider communication ...

    • Stigma trajectories among people living with HIV (PLHIV) embarking on a life time journey with antiretroviral drugs in Jinja, Uganda 

      Mbonye, Martin; Nakamanya, Sarah; Birungi, Josephine; King, Rachel; Seeley, Janet; Jaffar, Shabbar (BioMed Central Ltd., 2013-09-05)
      Background: Stigma is a barrier to HIV prevention and treatment. There is a limited understanding of the types of stigma facing people living with HIV (PLHIV) on antiretroviral therapy (ART). We describe the stigma ...

    • Strengthening district-based health reporting through the district health management information software system: the Ugandan experience 

      Kiberu, Vincent Micheal; Matovu, Joseph K. B.; Makumbi, Fredrick; Kyozira, Carol; Mukooyo, Eddie; Wanyenze, Rhoda K. (BioMed Central Ltd., 2014-05)
      Background: Untimely, incomplete and inaccurate data are common challenges in planning, monitoring and evaluation of health sector performance, and health service delivery in many sub-Saharan African settings. We document ...