Now showing items 1-20 of 122

    • Towards a National AIDS-Control Program in Uganda 

      Okware, Samuel Ikwaras (PubMed Central, 1987-12)
      A national AIDS-control program was developed in Uganda to deal with a potentially serious epidemic of the acquired immunodeficiency syndrome (AIDS). A cumulative total of 1, 138 cases of AIDS has been reported in Uganda ...
    • Quantitative process evaluation of a community-based HIV/AIDS behavioural intervention in rural Uganda. 

      Kanyesigye, E.; Kisman, J.; Kamali, A.; Kamulegeya, I.; Basajja, V.; Nakiyingi, J.; Schenk, K.; Whitworth, J. (2002)
      This paper describes the implementation of a large community-based HIV/AIDS behavioural intervention in rural Uganda and presents 4 years' worth of quantitative process data. The intervention involved 560 field-based workers ...
    • Infection of New- and Old-World Aedes albopictus (Diptera: Culicidae) by the Intracellular Parasite Wolbachia: Implications for Host Mitochondrial DNA Evolution 

      Armbruster, Peter; Damsky, William E.; Giordano, Rosanna; Birungi, Josephine; Munstermann, Leonard E.; Conn, And Jan E. (Journal of Medical Entomology, 2003)
      Wolbachia are cytoplasmically inherited, endosymbiotic bacteria known to infect a wide variety of arthropods. Polymerase chain reaction (PCR) ampliÞcation of the Wolbachia surface protein (wsp) gene was used to assay the ...
    • A good death in Uganda: survey of needs for palliative care for terminally ill people in urban areas 

      Kikule, Ekiria (2003-07)
      Objective To identify the palliative care needs of terminally ill people in Uganda. Design Descriptive cross sectional study. Setting Home care programmes in and around Kampala that look after terminally ill people in ...
    • Standardization of cytokine flow cytometry assays 

      Maecker, Holden T.; Rinfret, Aline; D'Souza, Patricia; Darden, Janice; Roig, Eva; Landry, Claire; Hayes, Peter; Birungi, Josephine; Anzala, Omu; Garcia, Miguel; Harari, Alexandre; Frank, Ian; Baydo, Ruth; Baker, Megan; Holbrook, Jennifer; Ottinger, Janet; Lamoreaux, Laurie; Epling, C. Lorrie; Sinclair, Elizabeth; Suni, Maria A.; Punt, Kara; Calarota, Sandra; El-Bahi, Sophia; Alter, Gailet; Maila, Hazel; Kuta, Ellen; Cox, Josephine; Gray, Clive; Altfeld, Marcus; Nougarede, Nolwenn; Boyer, Jean; Tussey, Lynda; Tobery, Timothy; Bredt, Barry; Roederer, Mario; Koup, Richard; Maino, Vernon C.; Weinhold, Kent; Pantaleo, Giuseppe; Gilmour, Jill; Horton, Helen; Sekaly, Rafick P. (BioMed Central Ltd., 2005-06-24)
      Background: Cytokine flow cytometry (CFC) or intracellular cytokine staining (ICS) can quantitate antigen-specific T cell responses in settings such as experimental vaccination. Standardization of ICS among laboratories ...
    • Repeat Voluntary HIV Counseling and Testing (VCT), Sexual Risk Behavior and HIV Incidence in Rakai, Uganda 

      Matovu, Joseph K. B.; Gray, Ronald H.; Kiwanuka, Noah; Kigozi, Godfrey; Wabwire-Mangen, Fred; Nalugoda, Fred; Serwadda, David; Sewankambo, Nelson K.; Wawer, Maria J. (Springer Science+Business Media, LLC, 2006)
      We examined the effects of repeat Voluntary HIV counseling and testing (VCT) on sexual risk behaviors and HIV incidence in 6,377 initially HIV-negative subjects enrolled in a prospective STD control for HIV prevention trial ...
    • Declining maternal mortality ratio in Uganda: priority interventions to achieve the Millennium Development Goal 

      Anthony, Mbonye; Miriam, Mutabazi; John Bosco, Asiimwe; Olive, Sentumbe; Jane, Kabarangira; G., Nanda; V., Orinda (Elsevier, 2007-05-21)
      Purpose: We conducted a survey to determine availability of emergency obstetric care (EmOC) and to provide data for advocating for improved maternal and newborn health in Uganda. Methods: The survey, covering 54 districts ...
    • Expanding access to voluntary HIV counselling and testing in sub-Saharan Africa: alternative approaches for improving uptake, 2001–2007 

      Matovu, Joseph K. B.; Makumbi, Fredrick E. (Tropical Medicine and International Health, 2007-11)
      The changing face of the HIV ⁄ AIDS epidemic has resulted in new opportunities to increase access to voluntary HIV counselling and testing (VCT), especially during the past 7 years (2001–2007). As access to HIV treatment ...
    • Use of WHO clinical stage for assessing patient eligibility to antiretroviral therapy in a routine health service setting in Jinja, Uganda 

      Jaffar, Shabbar; Birungi, Josephine; Grosskurth, Heiner; Amuron, Barbara; Namara, Geoffrey; Nabiryo, Christine; Coutinho, Alex (AIDS Research and Therapy, 2008-02-28)
      In a routine service delivery setting in Uganda, we assessed the ability of the WHO clinical stage to accurately identify HIV-infected patients in whom antiretroviral therapy should be started. Among 4302 subjects screened ...
    • Concordant Proficiency in Measurement of T-Cell Immunity in Human Immunodeficiency Virus Vaccine Clinical Trials by Peripheral Blood Mononuclear Cell and Enzyme-Linked Immunospot Assays in Laboratories from Three Continents 

      Boaz, Mark J.; Hayes, Peter; Tarragona, Tony; Seamons, Laura; Cooper, Andrew; Birungi, Josephine; Kitandwe, Paul; Semaganda, Aloysius; Kaleebu, Pontiano; Stevens, Gwynneth; Anzala, Omu; Farah, Bashir; Ogola, Simon; Indangasi, Jackton; Mhlanga, Patrick; Eeden, Melanie Van; Thakar, Madhuri; Pujari, Ashwini; Mishra, Shadri; Goonetilleke, Nilu; Moore, Stephen; Mahmoud, Abdul; Sathyamoorthy, Pattabiraman; Mahalingam, Jayashri; Narayanan, Paranji R.; Ramanathan, Vadakkuppattu D.; Cox, Josephine H.; Dally, Len; Gill, Dilbinder K.; Gilmour, Jill (Clinical and vaccine immunology, 2009-02)
      The gamma interferon (IFN-_) enzyme-linked immunospot (ELISPOT) assay is used routinely to evaluate the potency of human immunodeficiency virus (HIV) vaccine candidates and other vaccine candidates. In order to compare ...
    • CLSI-Derived Hematology and Biochemistry Reference Intervals for Healthy Adults in Eastern and Southern Africa 

      Karita, Etienne; Ketter, Nzeera; Price, Matt A; Kayitenkore, Kayitesi; Kaleebu, Pontiano; Nanvubya, Annet; Anzala, Omu; Jaoko, Walter; Mutua, Gaudensia; Ruzagira, Eugene; Mulenga, Joseph; Sanders, Eduard J.; Mwangome, Mary; Allen, Susan; Bwanika, Agnes; Bahemuka, Ubaldo; Awuondo, Ken; Omosa, Gloria; Farah, Bashir; Amornkul, Pauli; Birungi, Josephine; Yates, Sarah; Stoll-Johnson, Lisa; Gilmour, Jill; Stevens, Gwynn; Shutes, Erin; Manigart, Olivier; Hughes, Peter; Dally, Len; Scott, Janet; Stevens, Wendy; Fast, Pat; Kamali, Anatoli (2009-02-06)
      Background: Clinical laboratory reference intervals have not been established in many African countries, and non-local intervals are commonly used in clinical trials to screen and monitor adverse events (AEs) among African ...
    • Association between socio economic status and schistosomiasis infection in Jinja District, Uganda 

      Muhumuza, Simon; Kitimbo, George; Oryema-Lalobo, Michael; Nuwaha, Fred (Wiley Online Library, 2009-04-20)
      Objective: To examine the role of socioeconomic situation in influencing the risk and intensity of infection with Schistosomiasis mansoni. Methods: Cross-sectional study in Walukuba Division bordering Lake Victoria, Jinja ...
    • Mortality and loss-to-follow-up during the pre-treatment period in an antiretroviral therapy programme under normal health service conditions in Uganda. 

      Amuron, Barbara; Namara, Geoffrey; Birungi, Josephine; Nabiryo, Christine; Levin, Jonathan; Grosskurth, Heiner; Coutinho, Alex; Jaffar, Shabbar (BioMed Central Ltd., 2009-08-11)
      Background: In many HIV programmes in Africa, patients are assessed clinically and prepared for antiretroviral treatment over a period of 4–12 weeks. Mortality rates following initiation of ART are very high largely because ...
    • Rates of virological failure in patients treated in a home-based versus a facility-based HIV-care model in Jinja, southeast Uganda: a cluster-randomised equivalence trial 

      Jaffar, Shabbar; Amuron, Barbara; Foster, Susan; Birungi, Josephine; Levin, Jonathan; Namara, Geoffrey; Nabiryo, Christine; Ndembi, Nicaise; Kyomuhangi, Rosette; Opio, Alex; Bunnell, Rebecca; Tappero, Jordan W.; Mermin, Jonathan; Coutinho, Alex; Grosskurth, Heiner (Elsevier, 2009-12-19)
      Background: Identification of new ways to increase access to antiretroviral therapy in Africa is an urgent priority. We assessed whether home-based HIV care was as effective as was facility-based care. Methods: We undertook ...
    • The experience of “medicine companions” to support adherence to antiretroviral therapy: quantitative and qualitative data from a trial population in Uganda 

      Foster, S. D.; Nakamanya, S.; Kyomuhangi, R.; Amurwon, J.; Namara, G.; Amuron, B.; Nabiryo, C.; Birungi, Josephine; Wolff, B.; Jaffar, S.; Grosskurth, H. (Routledge Taylor & Francis Group, 2010-08-02)
      Good adherence is critical for antiretroviral therapy (ART) in sub-Saharan Africa. We report on the characteristics of medicine companions (MCs) chosen by Ugandan patients enrolling on ART, and on how MCs were chosen, and ...
    • A Phase 2 Study to Evaluate the Safety and Immunogenicity of a Recombinant HIV Type 1 Vaccine Basedon Adeno-Associated Virus. 

      Vardas, Eftyhia; Kaleebu, Pontiano; Bekker, Linda-Gail; Hoosen, Anwar; Chomba, Elwyn; Johnson, Philip R.; Anklesaria, Pervin; Birungi, Josephine; Barin, Burc; Boaz, Mark; Cox, Josephine; Lehrman, Jennifer; Stevens, Gwynn; Gilmour, Jill; Tarragona, Tony; Hayes, Peter; Lowenbein, Sarah; Kizito, Eva; Fast, Patricia; Heald, Alison E.; Schmidt, Claudia (Mary Ann Liebert, Inc., 2010-08-12)
      The recombinant vaccine, tgAAC09, based on an adeno-associated virus serotype 2 (AAV2) vector encoding HIV-1 subtype C Gag, protease, and part of reverse transcriptase, induced robust T cell and antibody responses in ...
    • Proportion of Deaths and Clinical Features in Bundibugyo Ebola Virus Infection, Uganda 

      MacNeil, Adam; Farnon, Eileen C.; Wamala, Joseph; Okware, Sam; Cannon, Deborah L.; Reed, Zachary; Towner, Jonathan S.; Tappero, Jordan W.; Lutwama, Julius; Downing, Robert; Nichol, Stuart T.; Ksiazek, Thomas G.; Rollin, Pierre E. (Emerging infectious disease, 2010-12)
      The first known Ebola hemorrhagic fever (EHF) outbreak caused by Bundibugyo Ebola virus occurred in Bundibugyo District, Uganda, in 2007. Fifty-six cases of EHF were laboratory confirmed. Although signs and symptoms were ...
    • Equivalence of ELISpot Assays Demonstrated between Major HIV Network Laboratories 

      Gill, Dilbinder K.; Huang, Yunda; Levine, Gail L.; Sambor, Anna; Carter, Donald K.; Sato, Alicia; Kopycinski, Jakub; Hayes, Peter; Hahn, Bridget; Birungi, Josephine; Tarragona-Fiol, Tony; Wan, Hong; Randles, Mark; Cooper, Andrew Raxworthy; Ssemaganda, Aloysius; Clark, Lorna; Kaleebu, Pontiano; Self, Steven G.; Koup, Richard; Wood, Blake; McElrath, M. Juliana; Cox, Josephine H.; Hural, John; Gilmour, Jill (PLOS ONE, 2010-12-14)
      Background: The Comprehensive T Cell Vaccine Immune Monitoring Consortium (CTC-VIMC) was created to provide standardized immunogenicity monitoring services for HIV vaccine trials. The ex vivo interferon-gamma (IFN-c) ELISpot ...
    • Mortality by baseline CD4 cell count among HIV patients initiating antiretroviral therapy: evidence from a large cohort in Uganda. 

      Mills, Edward J.; Bakanda, Celestin; Birungi, Josephine; Mwesigwa, Robert; Chan, Keith; Ford, Nathan; Hogg, Robert S.; Cooper, Curtis (Lippincott Williams & Wilkins, Inc., 2011)
      Objective: Evaluations of CD4 cell count and other prognostic factors on the survival of HIV patients in sub-Saharan Africa are extremely limited. Funders have been reticent to recommend earlier initiation of treatment. ...
    • Cohort Profile: The TASO-CAN Cohort Collaboration 

      Bakanda, Celestin; Birungi, Josephine; Nkoyooyo, Abdallah; Featherstone, Amber; Cooper, Curtis L; Hogg, Robert S; Mills, Edward J (International Journal of Epidemiology, 2011)
      Sub-Saharan Africa has scaled-up access to combination anti-retroviral therapy (cART) at unprecedented rates, yet data on patient-related outcomes remain sparse. Representative databases that facilitate high quality ...