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    • Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis 

      Dunn, Jessilyn; Qiu, Haiwei; Kim, Soyeon; Jjingo, Daudi; Hoffman, Ryan; Kim, Chan Woo; Jang, Inhwan; Son, Dong Ju; Kim, Daniel; Pan, Chenyi; Fan, Yuhong; Jordan, I. King; Jo, Hanjoong (American Society for Clinical Investigation, 2014)
      In atherosclerosis, plaques preferentially develop in arterial regions of disturbed blood flow (d-flow), which alters endothelial gene expression and function. Here, we determined that d-flow regulates genome-wide DNA ...